Friday, January 4, 2013

Use for old Christmas trees? Douglas fir needles may sterilize nano devices for medical applications

Jan. 2, 2013 ? As Twelfth Night approaches and the Christmas decorations start to look old, as the last crumbs of cake are swept away and the remnants of the turkey have finally been consumed, there is the perennial question as to what to do with the tree. Research published in the International Journal of Biomedical Nanoscience and Nanotechnology suggests that the needles of the plant Pseudotsuga menziesii, commonly known as the Douglas fir could be used to sterilize nano devices destined for medical applications.

Chemist Poushpi Dwivedi of MNNIT in Allahabad, India, and colleagues explain that one of the most troubling problems in biomedicine is bacterial infection at the site of implanted medical devices, prosthetics and sensors. They explain that despite advances in sterilization procedures and aseptic measures pathogenic microbes can still invade biomaterials and tissues. The researchers are developing an antimicrobial, self-sterilizing composite material derived from Douglas fir needles that is essentially a silver/chitosan bionanocomposite that can be used to safely coat medical implants and surgical devices to preclude microbial growth.

The team points out that silver nanoparticles have been tested widely for their potential as antimicrobial agents given that silver is well known to have bactericidal properties. They point out that using biological agents has come to the fore as an efficient and effective way to make novel types of silver nanoparticles with uniform size and shape and biocompatible surfaces for use in medicine. The team has now used an extract from Pseudotsuga menzietii together with silver nitrate solution to generate nanoparticles. These particles can then be readily dispersed in chitosan polymer to make a material that can coat metals and other materials. The plant extract acts as a natural chemical reducing agent to convert the silver ions in the nitrate solution to nanoscopic silver metal particles.

"The size and the percentage of the particles produced can be easily controlled, according to the requirement, by the initial concentration of the metal precursor and volume of the plant biomass," the team explains. So, as you are sweeping up the last fallen needles from your Christmas tree come Twelfth Night, think on, those needles could underpin the next medical shot in the arm.

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The above story is reprinted from materials provided by Inderscience Publishers, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Poushpi Dwivedi, S.S. Narvi, R.P. Tewari. Potentiality of the plant Pseudotsuga menzietii to combat implant-related infection in the nanoregime. International Journal of Biomedical Nanoscience and Nanotechnology, 2012; 2 (3/4): 187 DOI: 10.1504/IJBNN.2012.051217

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/--E7G2XK8KY/130102140445.htm

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Wednesday, January 2, 2013

Woman Dies on Plane From Brazil to Texas

Source: http://www.thehollywoodgossip.com/2013/01/woman-dies-on-plane-from-brazil-to-texas/

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Canadians focused on paying down debt: poll - tonight Newspaper ...

Canadians focused on paying down debt: poll

2 January 2013 No Comment

Hugh McKenna, The Canadian Press | Last Updated:Wed, 02 Jan 2013 22:51:19 GMT

TORONTO - Canadians appear less concerned about retirement planning than in years past as they continue to focus on debt reduction as their main financial priority, according to a new study released Wednesday by CIBC (TSX:CM).

Overall, the poll done for the bank by Harris/Decima showed 17 per cent of respondents selected debt reduction as their main priority in 2013, unchanged from 2012 and the third year in a row that it has topped the list. Fourteen per cent chose debt reduction in 2011.

But while paying down debt topped the list, it remains to be seen how much progress Canadians will make in accomplishing that goal.

Despite having the same priority last year, Statistics Canada says the household debt to income ratio actually rose to a record high 164.6 per cent in 2012.

Meanwhile, the poll involving more than 2,000 adults 18 years of age and over found that retirement planning was no longer among the top three on the list of priorities among Canadians surveyed.

It was selected by only seven per cent of respondents overall, down from 11 per cent last year and 13 per cent in 2011.

Second on the list ? chosen by 10 per cent overall and unchanged from last year ? was building savings. Managing day-to-day spending/budgeting came in third, selected by eight per cent of respondents and down from 14 per cent last year.

"A key finding of the poll is that age groups where retirement planning was traditionally a top priority have now shifted to a focus on debt reduction," CIBC said.

Two years ago, 24 per cent of respondents aged 45-64 named retirement planning as their top financial priority, which fell to just 12 per cent among that age group in this year's survey.

At the same time, debt management increased as a priority for that age group to 18 per cent from 14 per cent.

"While it is important to address immediate financial needs such as debt reduction, it is equally important to keep long-term goals such as retirement in sight," bank spokeswoman Christina Kramer said in a comment accompanying the results.

"Even small contributions today can make it easier in future years to reach your retirement savings goals," said Kramer, executive vice-president, retail distribution and channel strategy.

Still, Kramer said the survey results highlight that Canadians are "well aware of the importance of good debt management."

"Having been named the top priority three years in a row, there is an opportunity for more Canadians to turn awareness of debt management into action and outline some clear steps towards paying down their debt in 2013," she said.

Kramer said that while it can be challenging to keep multiple financial goals top of mind "it is possible to make debt repayment a priority while still keeping up regular investments into your retirement plan."

Among other things, she said people should recognize that their finances are all connected and that making progress on one aspect of a person's financial goals can lead to an opportunity to improve in others as well.

The Harris/Decima telephone survey, conducted between Oct. 25 and Nov. 4, involved 2,009 adults 18 years of age and over and is considered to have a margin of error of plus or minus 2.2 percentage points 19 times out of 20.

Source: http://www.tonightnewspaper.com/2013/01/02/canadians-focused-on-paying-down-debt-poll/

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New study documents the natural relationship between CO2 concentrations and sea level

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Source: http://www.eurekalert.org/pub_releases/2013-01/nocs-nsd010213.php

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Tuesday, January 1, 2013

Breaking: Hillary Clinton Hospitalized After Blood Clot Discovered (Little green footballs)

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Space travel may be harmful to the brain, study suggests; Prolonged cosmic radiation exposure could hasten Alzheimer's

Dec. 31, 2012 ? As if space travel was not already filled with enough dangers, a new study out today in the journal PLOS ONE shows that cosmic radiation -- which would bombard astronauts on deep space missions to places like Mars -- could accelerate the onset of Alzheimer's disease.

"Galactic cosmic radiation poses a significant threat to future astronauts," said M. Kerry O'Banion, M.D., Ph.D., a professor in the University of Rochester Medical Center (URMC) Department of Neurobiology and Anatomy and the senior author of the study. "The possibility that radiation exposure in space may give rise to health problems such as cancer has long been recognized. However, this study shows for the first time that exposure to radiation levels equivalent to a mission to Mars could produce cognitive problems and speed up changes in the brain that are associated with Alzheimer's disease."

While space is full of radiation, the earth's magnetic field generally protects the planet and people in low earth orbit from these particles. However, once astronauts leave orbit, they are exposed to constant shower of various radioactive particles. With appropriate warning, astronauts can be shielded from dangerous radiation associated with solar flares. But there are also other forms of cosmic radiation that, for all intents and purposes, cannot be effectively blocked.

Because this radiation exists in low levels, the longer an astronaut is in deep space, the greater the exposure. This is a concern for NASA as the agency is planning manned missions to a distant asteroid in 2021 and to Mars in 2035. The round trip to the red planet, in particular, could take as long as three years.

For over 25 years, NASA has been funding research to determine the potential health risks of space travel in an effort to both develop countermeasures and determine whether or not the risks warranted sending men and women on extended missions in deep space.

Since that time, several studies have demonstrated the potential cancer, cardiovascular, and musculoskeletal impact of galactic cosmic radiation. The study out today for the first time examines the potential impact of space radiation on neurodegeneration, in particular, the biological processes in the brain that contribute to the development of Alzheimer's disease. O'Banion -- whose research focuses on how radiation affects the central nervous system -- and his team have been working with NASA for over eight years.

The researchers studied the impact of a particular form of radiation called high-mass, high-charged (HZE) particles. These particles -- which are propelled through space at very high speeds by the force of exploding stars -- come in many different forms. For this study the researcher chose iron particles. Unlikely hydrogen protons, which are produced by solar flares, the mass of HZE particles like iron, combined with their speed, enable them to penetrate solid objects such as the wall and protective shielding of a spacecraft.

"Because iron particles pack a bigger wallop it is extremely difficult from an engineering perspective to effectively shield against them," said O'Banion. "One would have to essentially wrap a spacecraft in a six-foot block of lead or concrete."

A portion of the research was conducted at the NASA Space Radiation Laboratory at Brookhaven National Laboratory on Long Island. NASA located its research operation at Brookhaven to take advantage of the Lab's particle accelerators which -- by colliding matter together at very high speeds -- can reproduce the radioactive particles found in space.

The researchers specifically wanted to examine whether or not radiation exposure had the potential to accelerate the biological and cognitive indicators of Alzheimer's disease, particularly in individuals who may be predisposed to developing the disease. To accomplish this they chose study the impact on animal models of Alzheimer's disease. These particular models have been extensively studied and scientists understand the precise timeframe in which the disease progresses over time.

At Brookhaven, the animals were exposed to various doses of radiation, including levels comparable to what astronauts would be experience during a mission to Mars. Back in Rochester, a team of researchers -- including URMC graduate student Jonathan Cherry, who was first author on the paper -- evaluated the cognitive and biological impact of the exposure. The mice underwent a series of experiments during which they had to recall objects or specific locations. The researchers observed that mice exposed to radiation were far more likely to fail these tasks -- suggesting neurological impairment -- earlier than these symptoms would typically appear.

The brains of the mice also showed signs of vascular alterations and a greater than normal accumulation of beta amyloid, the protein "plaque" that accumulates in the brain and is one of the hallmarks of the disease.

"These findings clearly suggest that exposure to radiation in space has the potential to accelerate the development of Alzheimer's disease," said O'Banion. "This is yet another factor that NASA, which is clearly concerned about the health risks to its astronauts, will need to take into account as it plans future missions."

Additional co-authors include Jacqueline Williams, Ph.D. and John Olschowka, Ph.D. with URMC and Bin Liu, Ph.D., Jeffrey Frost, and Cynthia Lemere, Ph.D. with Harvard Medical School. The study was funded by NASA.

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Story Source:

The above story is reprinted from materials provided by University of Rochester Medical Center.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Jonathan D. Cherry, Bin Liu, Jeffrey L. Frost, Cynthia A. Lemere, Jacqueline P. Williams, John A. Olschowka, M. Kerry O?Banion. Galactic Cosmic Radiation Leads to Cognitive Impairment and Increased A? Plaque Accumulation in a Mouse Model of Alzheimer?s Disease. PLoS ONE, 2012; 7 (12): e53275 DOI: 10.1371/journal.pone.0053275

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/space_time/astronomy/~3/KBZnKWpQ1Gk/121231180632.htm

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